Research activity

The main research field of the Department is heterocyclic chemistry including

  • synthesis, chemical, physico-chemical properties and theoretical aspects of potentially bioactive nitrogen-containing heterocyclic compounds,

  • methodological studies on and applications of organometallic chemistry, ring closure reactions for the synthesis of polycyclic compounds,

  • medicinal chemistry of cardiovascular and central nervous systems (antiarrhythmic agents, compounds effecting on NMDA-receptor system, respectively), G-protein coupled cationic neurotransmitter receptors, semicarbazide-sensitive amine oxidase inhibitors,

  • isolation, structure determination and chemical transformation of natural products, in particular iridoids,

  • design of bioactive compounds by 3D QSAR and neural network,

  • studies of ADME properties by computational methods,

  • aspects of computational chemistry.

 

Domestic and international collaborations

Both in research and education, the Department is cooperating with several institutions (academic and industrial) inside the country including Universities of Debrecen (Prof. S. Antus), Szeged (Profs. A. Varró, Gy. J. Papp, F. Fülöp, Gy. Falkay, I. Erős, K. Hódi, G. Regdon), Budapest University of Technology and Economics (Prof. Gy. Keglevich), Research Center for Chemistry of Hungarian Academy of Sciences (Prof. Gy. Hajós, Zs. Riedl), IVAX Institute for Drug Research (A. Simay, K. Horváth), EGIS Pharmaceutical Company (Prof. L. Hársing); as well as with Universities of Vienna (Prof. N. Haider), Antwerp (Profs. B. Maes, G. Lemiére), Leuven (Prof. E. Van der Eycken), Cagliari (Prof. A. Fadda), Palermo (Prof. G. Cirrincione), Milan (Prof. D. Barlocco).

 

Visiting Professors

2005. Prof. Henk Timmerman (Vrije Universiteit, Amsterdam)
Prof. Carlo de Micheli (University of Milan)
Prof. Giuseppe Ronsisvalle (University Catania)
Prof. Marco de Amici (University Milan)
Prof. Girolamo Cirrincione (University Palermo)
Prof. Gaetamo Dattolo (University Palermo)
Prof. Ugo Chiacchio (University Catania)
Prof. Roberto Pellicciari (University Perugia)
Prof. Gerhard F. Ecker (University of Wien)
Prof. Ferran Sanz (Universitat Pompeu Fabra Barcelona)

2006. Prof. Bert Maes (University of Antwerp)
Prof. Norbert Haider (University of Wien)
Prof. Gerhard F. Ecker (University of Wien)
Prof. Christina Chai (A*STAR Institute of Chemical and Engineering Sciences, Singapure)

2007. Prof. Danijel Kikelj (University Ljubljana)
Prof. Anna Fadda (University of Cagliari)
2008. Prof. George Olah (University of Southern California, Los Angeles, CA, USA)

 

Visiting Students/PhD Students

Andrea Pinto, 2005, Univ Milano
Christina Bonamico, 2005, Univ. Torino
Carla Mura, 2006, Univ. Cagliari
Simone Atzori, 2006, Univ. Cagliari
Andrea Wobus, 2006, Univ. Wien
Guido Catania, 2007, Univ. Palermo
Osvaldo Cancellu, 2007, Univ. Cagliari
Giuseppe Bongiovanni, 2007, Univ. Palermo
Antonino Grillo, 2008, Univ. Catania
Szende Váncsa , 2008, Marosvásárhelyi Egyetem